Table of contents
- What is Janumet Tablet?
- Composition & Strength of Janumet Tablet
- How Janumet tablet works?
- Janumet Tablet uses
- Common side effects of Janumet tablet
- Janumet Contraindications
- Precautions & How to Use Janumet
- Dosage of Janumet
- General warnings
- Alternative tablets for Janumet
What is Janumet Tablet?
Janumet is an oral anti-diabetic drug which is used to treat type 2 diabetes mellitus. It reduces high blood sugar level. The medication is taken along with the controlled diet and exercise. Read on to know about working, side effects, precautions, and contraindications of Janumet Tablets.
Composition & Strength of Janumet Tablet
The active ingredients of Janumet Tablet are Metformin and Sitagliptin. Janumet contains 500 mg Metformin and 50 mg Sitagliptin for oral use.
How Janumet tablet works?
Janumet tablet is a composition of two antidiabetic medicine; Metformin and Sitagliptin. Metformin is an oral antihyperglycemic agent. It decreases the blood glucose level by increasing the sensitivity of liver, muscle, fat and other tissues to the effect of insulin. Due to this increase, the sensitivity of tissues to insulin increases that leads to increased peripheral glucose uptake and utilization. Thus this process leads to a decrease in the blood sugar level.
Sitagliptin acts by increasing the level of incretin hormones such as glucagon-like peptide-1(GLP-1) and glucose-dependent insulinotropic polypeptide(GIP) after a meal from the intestine. This results in increasing the production and release of insulin from the pancreas and causing the sugar level in the blood to decrease.
Janumet Tablet uses
Janumet Tablet is used in patients suffering from the conditions:
Non-Insulin Dependent Diabetes Mellitus:
A condition in which our pancreas does not produce a sufficient amount of insulin due to which increased the blood sugar level.
Common side effects of Janumet tablet
- Sore throat
- Abdominal pain
- Running nose
- Respiratory tract infection
Janumet – Contraindications
Following are the conditions when the usage of Janumet is not advised:
- Hypersensitivity to Janumet tablet or any of the excipients
- Diabetic ketoacidosis and lactic acidosis
- Diabetic pre-coma
- Several renal failures
- Acute and chronic disease such as cardiac or respiratory failure, any history of myocardial infarction and shock
Janumet – Precautions & How to Use
Before taking Janumet tablet, tell your doctor/pharmacist about your medication of prescription and nonprescription. If you had an allergic reaction to Janumet tablet or any other related drug you should share with doctors/pharmacist. Must be mention if you are taking or plan to take angiotensin-converting enzymes inhibitors such as benazepril, enalapril, lisinopril, ramipril or any anticoagulants such as warfarin, aspirin or any NSAIDs such as ibuprofen, naproxen or any other diabetic medication.
Janumet tablet is not suitable for some people so, ask your doctor/pharmacist about the benefits and risks of this drug before taking :
- If you are suffering from kidney diseases
- If you are suffering from diabetic ketoacidosis
- Any history of myocardial infarction and shock
Dosage of Janumet
Dose should be decided by the doctor depending upon severity of condition. Take the prescribed dose. Do not change or stop the medications without consulting your doctor. Swallow this medicine with water.
Do not take more than prescribed dose it may cause harmful side effects. Symptoms of overdose may be an irregular heartbeat, diarrhea, nausea, drowsiness. So consult your doctor or pharmacist if you find any side effects.
If you miss a dosage take it as soon as possible. Do not take it if it is near the time for the next dose, skip the missing dosage continue the regular dosage. Never use an extra dose to make up the missed one.
There is no adequate data available about toxicity in a pregnant lady. Some animal studies have shown that Janumet harm the fetus. Consult your doctor/pharmacist before taking this medicine
Before taking this medicine consult your doctor/ pharmacist, if you are breastfeeding.
Alternative tablets for Janumet
The alternative tablets have the same composition, strength, and form as Janumet Tablet they are the following :
- Istamet tablet 500MG/50MG – Manufactured by Sun Pharmaceutical Industries
- Zitamet tablet 500MG/50MG – Manufactured by Glenmark Pharmaceuticals
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