The report titled “Lip Cancer Global Clinical Trials Review H2 2017”, provides a comprehensive analysis of lip cancer, causes, various treatments, Mohs micrographic surgery, leading players, basics of clinical trials and phases, impact of lip cancer, modernization and evolution in medical science will detect lip cancer at early stage in the coming years.
Lip Cancer Overview: Lip cancer is disruptive growth of cells which form injuries or tumors on the lips. Lip cancer is also known as the most common type of oral cancer. It develop in thin, flat cells known as squamous cells that line the lips, mouth, tongue, cheeks, sinuses, throat, and hard and soft palates. Modern lifestyle choices, such as smoking, drinking, sun exposure, and tanning, increase the risk of developing lip cancer. The first signs of lip cancer are noticed by the dentists during any routine dental examination. If diagnosed early lip cancers are highly curable. It was observed that more than 36,000 people globally are diagnosed with oral cancer every year.
Factors, Symptoms, Available Treatments and Prevention of Lip Cancer: Major factors that increase the risk for lip cancers include smoking or using tobacco products (cigarettes, cigars, pipes, or chewing tobacco), heavy use of alcohol, exposure to direct sunlight (both natural and artificial), including the use of tanning beds, over long periods, infection with human papillomavirus (HPV), a sexually transmitted virus and above 40 years of age as well as cases of immune-suppression. The symptoms of lip cancers are sore, lesion, blister, ulcer, or lump on the mouth that does not go away, a red or white patch on the lip, bleeding or pain on the lips and swelling of the jaw. The various treatments available for lip cancer are surgery, radiation therapy, chemotherapy, immunotherapy, cryotherapy (freezing with liquid nitrogen) and gene therapy. The treatment depends on the stage of the lip cancer and the size of the tumor. Surgery is performed to remove if it is a small tumor. If the tumor is large or at a later stage, radiation and chemotherapy treatments are used to shrink the tumor to reduce the risk of re-ocurrence. Lip cancer can be prevented by avoiding all types of tobacco, alcohol intake, and limiting exposure to both natural and artificial sunlight.
Mohs micrographic surgery is commonly used to treat lip cancer which involves removing thin layers of skin tissue, which are then colour-coded, mapped, and microscopically examined. If cancer cells are detected, more tissue from the affected area is removed and the process is repeated until no more cancer can be found. This surgery offers the highest cure rate of any treatment modalities for primary or recurrent lip tumors. Emergency treatment is recommended for cases where lip cancer has spread and is known to interfere with the function of a vital organ. Men are at a greater risk than women in occurrence of lip cancer. Lip cancer diagnostic tests involve physical examination for sores, lumps or mouth ulcers. Biopsy, X-rays and CT scans are also done to determine the spread of lip cancer. Other diagnostic tests include endoscopy, exfoliative cytology, Magnetic Resonance Imaging (MRI), barium swallow, PET scan and bone scan.
Geography and Leading Players in Lip Cancer: To reduce the risk of lip cancer, doctors prescribe regular use of photo protective lip blocks (lip products that contain sunscreen) because they help reduce exposure to U.V. radiation. Lip cancer market is geographically spread across North America, Europe, Asia Pacific and Rest of the World. The Unites States ranks first in lip cancer cases, followed by Asia-Pacific with considerable number of lip cancer cases. The leading players in global lip cancer market are Astra Zeneca plc, Bristol Myers Squibb, Celgene, Eli Lilly & Co., Hofmann La Roche, Pfizer, Sanofi Aventis, Teva Pharmaceuticals, and Novartis AG.
Clinical Trials for Lip Cancer Involves Four Phases: Clinical trials are research studies that compare the most effective known treatment for a specific type or stage of cancer with a new approach. It can be a new drug, or combination of drugs or a different way of using the already established therapies. There are clinical trials for every type of cancer, to prevent cancer, improve early diagnosis, stop the cancer from coming back, reduce side effects or improve quality of life.
The first phase is where the drug is approved for human consumption and is tested in a small trial to determine the optimal safe dose which often involves patients with different kinds of cancer. In second phase, the approved drug is tested on cases with multiple cancers to determine the optimal dosing and provide an early assessment of whether the drug works. The third phase involves hundreds, or even thousands of patients, in multiple centres with specific types and stages of cancer. This stage provides definitive evidence to support the approval of the drug for use in the public. The phase four is known as post-marketing trials where the goal is to make sure that no safety or other concerns come up after a drug is approved that may not have been seen in the pre-approval trials.
Future of Global Lip Cancer Clinical Trials: It was observed that lip cancer clinical trials are collated from 80 plus different clinical trial registries, conferences, journals, news, etc across the globe. The lip cancer clinical trials database undergoes periodic update. Lip cancer is not only claiming lives but has a huge impact on the global economy. It also highlights the urgency of tackling preventable cancers globally. With increasing modernization and evolution in medical science, lip cancer is expected to be treated at an early stage with less pain and cost over the coming years.
Key Topics Covered in the Report:
Global Lip Cancer Clinical Trials Market Research Report
Global Lip Cancer Clinical Trials Market Size
Global Lip Cancer Clinical Trials Market Outlook
Global Lip Cancer Clinical Trials Market Forecast
Cancer industry clinical Trials
Global Lip Cancer Clinical Trials Market Analysis
Central Lip Cancer Therapeutics Clinical Trials
Europe Lip Cancer Therapeutics Clinical Trials
North America Lip Cancer Therapeutics Clinical Trials
Middle East Lip Cancer Therapeutics Clinical Trials
Asia Lip Cancer Therapeutics Clinical Trials
Lip Cancer Clinical Trials and Average Enrollment by Top Countries
South America Lip Cancer Therapeutics Clinical Trials
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Ankur Gupta, Head Marketing & Communications