Ferroptosis, a form of programmed cell death characterized by iron-dependent lipid peroxidation, is a promising avenue in cancer therapy. New research shows that disrupting cancer cells' lip… Read More
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This website explores the potential of synergistic combinations of natural substances, repurposed drugs, and conventional treatments for combating cancer.
Monoamine oxidase A (MAO-A), an enzyme historically studied for its role in neurotransmitter metabolism, has emerged as a promising target in cancer immunotherapy. By inhibiting MAO-A, resea… Read More
This study, a collaboration between researchers from the Netherlands Cancer Institute, Wellcome Sanger Institute (UK), Delft University of Technology, and Oncode Institute, outlines a compre… Read More
Orlistat, developed initially and FDA-approved as an anti-obesity drug, inhibits pancreatic and gastric lipases, thereby reducing dietary fat absorption. However, emerging research over the… Read More
Researchers at Emory University's Winship Cancer Institute have uncovered a previously unknown immune cell type, a stem-like CD4 T cell, which shows promise to improve cancer imm… Read More
Across various cancer types and contexts, metformin has demonstrated promising anti-tumor mechanisms that include modulating cellular energy metabolism, enhancing immune response… Read More
Phenylbutyrate (PB), a short-chain fatty acid derivative, is primarily recognized as an ammonia scavenger and histone deacetylase inhibitor (HDACi). Initially developed for managing urea cyc… Read More
Niclosamide, approved initially as an anthelmintic, has garnered significant attention in oncology for its anticancer potential. The repositioning of niclosamide is particularly appealing du… Read More
Two studies, Jin et al. and Lee et al., provide a detailed look into the role of high dietary inorganic phosphate (Pi) in promoting lung tumorigenesis, revealing both early and long-term eff… Read More
Lung cancer driven by KRAS mutations, particularly the G12C variant, remains a significant challenge in non-small cell lung cancer (NSCLC) treatment. KRAS mutations promote tumor growth and… Read More
Itraconazole, a widely used antifungal medication, has emerged as a potential repurposed drug for cancer treatment. Beyond its antifungal properties, itraconazole has effectively inhibited c… Read More
Fasting has long been recognized as a natural strategy for enhancing health, with numerous studies demonstrating its benefits for inhibiting cancer progression. However, prolonged fasting ca… Read More
The study titled "AHCC®, a Standardized Extract of Cultured Lentinula Edodes Mycelia, Promotes the Anti-Tumor Effect of Dual Immune Checkpoint Blockade Effect in Murine Colon Canc… Read More
The review article "A Review on Ferroptosis and Photodynamic Therapy Synergism: Enhancing Anticancer Treatment" looks at the potential synergy between two innovative cancer therapies: ferrop… Read More
The paper "Computational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data" takes a computational approach to identifying natural compoun… Read More
The article “Stable triangle: nanomedicine-based synergistic application of phototherapy and immunotherapy for tumor treatment†published by Cai et al. i… Read More
Ammonia use in household products like cleaning agents has declined over the years due to safety concerns and the rise of eco-friendly alternatives. While there aren't specific historical da… Read More
The review article "Multi-stage Mechanisms of Tumor Metastasis and Therapeutic Strategies" provides a detailed review of cancer metastasis, a leading cause of cancer-related mortality.Â… Read More
Repurposing non-oncology drugs for cancer treatment has become an area of increasing interest. In particular, combinations of well-known pharmaceuticals are being explored to enhance antican… Read More
Disulfiram acts as both a direct cytotoxic agent and an immunomodulator, making it a good candidate for combination therapies in cancer treatment.Immunomodulation: DSF enhances the immune re… Read More
The article “Targeting the Mitochondrial-Stem Cell Connection in Cancer Treatment: A Hybrid Orthomolecular Protocol†introduces a novel approach to cance… Read More
Chronic stress has been increasingly recognized as a significant risk factor for various cancers, including colorectal cancer (CRC). Here are three studies that looked at the role of chronic… Read More
 "A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers" by Alruwaili et al., 2024, studie… Read More
The authors of this study investigated the potential of chrysin, a natural flavonoid, in enhancing radiation therapy (RT)-induced immunogenic cell death (ICD) in melanoma cells, specifically… Read More
Drug repurposing leverages existing drugs, initially designed for other conditions like diabetes, as potential cancer therapies. This approach has numerous advantages, including reduced deve… Read More
Autophagy, a cellular process responsible for degrading unnecessary or damaged cellular components, has a complex role in cancer development and treatment. Under normal conditions, autophagy… Read More
Turmeric and its primary active ingredient, curcumin, have garnered significant interest due to its potential role in augmenting radiation therapy in cancer treatment. Research indicates tha… Read More
The findings of this study indicate that the combination of pazopanib and metformin could be a promising therapeutic strategy for lung cancer treatment.NSCLC is the most common t… Read More
Given the importance of T cell immunity and the gut microbiome in modulating immune responses, the researchers in this study hypothesized that the intestinal microbiome might affect the outc… Read More
Dasatinib, a multi-kinase inhibitor, has demonstrated effectiveness against various solid tumors, including lung cancer, by inhibiting SRC family kinases (SFKs). However, dasatinibâ&eu… Read More
Chronic myeloid leukemia (CML) has seen significant advancements with the introduction of tyrosine kinase inhibitors (TKIs), such as dasatinib (Sprycel®). However, dasatinib's bio… Read More
The conventional genetic theory of cancer remains one of the most widely accepted explanations for tumor development. It asserts that mutations in oncogenes and tumor suppressor genes accumu… Read More
Boswellia serrata, commonly known as frankincense, is a natural resin extracted from the Boswellia tree, widely used for its medicinal properties. In preclinical studies, boswellic acids, th… Read More
Traditionally, 5-fluorouracil (5-FU) has been used in combination with DNA-damaging chemotherapy drugs like oxaliplatin and irinotecan to treat colorectal cancer (CRC). However, in this stud… Read More
The combined inhibition of KRASG12C and mTORC1 kinase has emerged as a promising strategy for treating non-small cell lung cancer (NSCLC), particularly in cases where KRASG12C mutations are… Read More
El amonÃaco (NH3) está compuesto por un átomo de nitrógeno y tres átomos de hidrógeno, mientras que el ion amo… Read More
Around 80% of breast cancers are estrogen-receptor positive, meaning they rely on estrogen to grow. These cancers are often treated with hormone therapies like tamoxifen or aromatase inhibit… Read More
Chris Ward, founder of ChrisBeatCancer.com, is a well-known figure in the alternative health and cancer recovery community. His journey began after being diagnosed with stage III colon cance… Read More
Fusobacterium nucleatum and Streptococcus anginosus have been associated with cancers of the gastrointestinal tract, including colorectal and esophageal tumors.Concerns have been raised by s… Read More
The treatment for glioblastoma (GBM), a highly aggressive type of brain tumor, typically involves a multi-modal approach, combining surgery, radiation therapy, and chemotherapy. … Read More
Fenbendazole, part of the benzimidazole carbamate drug family, is commonly used to treat parasitic infections in animals and humans. Its mechanism of action involves the inhibition of microt… Read More
1. What is Ivermectin, and what is it typically used for?Ivermectin is an FDA-approved drug primarily used to treat parasitic infections caused by worms, such as intestinal strongyloidiasis… Read More
Natural supplements can be very helpful adjuvants to drug therapies, for example through chemosensitization of tumor cells. Unfortunately, it seems that very often there's little or no follo… Read More
AHCC 🛈Allicin 🛈Aloe Vera 🛈Andrographis extract ðŸ›&cir… Read More
This page lists several repurposed drugs (such as Niclosamide, Celecoxib, Phenylbutyrate, Tamoxifen, Metformin, etc.) that show potential in inhibiting cancer cell proliferation, inducing ap… Read More
A fundamental characteristic of cancer cells is their inclination toward anaerobic respiration leading to the conversion of glucose into lactic acid instead of… Read More
This "protocol" is an attempt to address some of the points raised in this post (Theory of Cancer - limit the consequences of glycolysis & help restore the oxygen and carbon dioxide depr… Read More
A new study suggests that red and processed meats may be contributing to the rising risk of colon cancer in young adults. {article}"Younger colon cancer patients typically have higher levels… Read More
In a study published two days ago, researchers discovered that ammonia enters cells via the SLC4A11 transporter and acts as a nitrogen source for the biosynthesis of… Read More
https://pubmed.ncbi.nlm.nih.gov/39096436/In this study published a few days ago, researchers found that CRC patients exhibit a significant decrease in Bifidobacterium abundance.When Bifidoba… Read More
About 90% of deaths from cancer are a result of metastasis. This article discusses Dr. Dana Pe'er's research on cellular plasticity and its role in cancer metastasis.She explains how cancer… Read More
 This Washington Post advertisement appeared a few months after the first landing on the moon (1969). It quoted Dr. Sidney Farber, oncologist and past president of the American C… Read More
Functional profiling for cancer is a method used in oncology to assess how cancer cells respond to various drugs or treatments based on their functional characteristics. Unlike genetic profi… Read More
In this study, the researchers defined high-intensity exercise as an exercise where your heart rate is 80-85% of the maximum pulse rate e.g. 132 for a 55-year-old. (How to Determine Your Max… Read More
Data from the ENGOT-OV16/NOVA study show NO difference in overall survival (OS) for patients with platinum-sensitive recurrent ovarian cancer who received poly (ADP-ribose) polymerase (PARP)… Read More
Treatment will depend on the stage of the cancer and may include surgery, chemotherapy, and radiation.SurgeryCYTALUXâ„¢:Â FDA-approved prescription medication tha… Read More
An analysis of data from approximately 9,000 Belgian patients by the Agence Intermutualiste offers a new reading on the intended target. It seems that half of the patients who received Opdiv… Read More
Note: I made this infographic in 2018 when my blog was still at anticancersupplements.blogspot. I moved to this blog since Read More
A gel completely cured mice with deadly brain cancer, a startling finding that gives patients with glioblastoma - one of the deadliest and most prevalent brain tumors in humans - new hope&Ac… Read More
In this study, in vivo therapeutic silencing of the ATF4-FAM129A axis markedly inhibited tumor growth in a preclinical PCa model.Ursolic acid and Tomatidine, as potential agents and/or lead… Read More