There are three main classes of Otc Medications for Pain and fever.
Acetaminophen (Tylenol) is used for pain and fever. It is not good for inflammation as other drugs, but is very effective for pain and fever.
NSAID's (Advil, Motrin, Aleve, etc.) are used for pain and fever but they also have the ability to decrease inflammation which is an added benefit if needed for your condition (arthritis pain or injury). They may irritate your stomach so please take with food to help avoid this problem.
Aspirin (Bayer, Bufferin, etc.) is used for pain, fever and inflammation. It may also irritate your stomach so take with food. Aspirin is sometimes taken on a daily basis on the recommendation of a Physician to help prevent heart attacks or stokes. Avoid aspirin for children.